PROGNOSIS IN BRONCHOPULMONARY SEQUESTRATION

The postnatal outcome correlates with the presence or absence and severity of associated anomalies, pulmonary hypoplasia and hemodynamic disturbances (1).

• Intralobar sequestration - excellent prognosis.
• Extralobar sequestration - poor prognosis based upon the higher incidence of serious associated anomalies and the development of hydrops fetalis.
• Spontaneous regression in utero has been reported (2-5). In up to 65% of cases it may decrease in size or even disappear before birth (3,6).

ALGORITHM FOR EVALUATION AND MANAGEMENT OF

PRENATALLY DIAGNOSES PULMONARY SEQUESTRATION

Obsterics and Gynecology 1999;94(4):567-571

References

1. Savic B, Britel FJ, Tholen W et.al. Lung sequestration: Report of seven cases and review of 540 published cases. Thorax 1979;34:96-101.
2. Langer B, Donato L, Rietmuller C et.al. Spontaneous regression of fetal pulmonary sequestration. Ultrasound Obstet Gynecol 1995;6:33-39.
3. Smulian JC, Guzman ER, Ranzini A et.al. Color and duplex doppler sonographic investigation of in utero spontaneous regression of pulmonary sequestration. J Ultrasound Med 1996;15:789-792.
4. MacGillivray TE, Harrison MR, Goldstein RB et.al. Disappearing fetal lung lesions. Pediatr Surg 1993;28:1321.
5. Sakala EP, Furness ME, Perrott WA et.al. Spontaneous in utero regression of antenatally diagnosed solid fetal chest masses: A report of two cases. J Reprod Med 1994;39:531.
6. Luet'ic T, Crombleholme TM, Semple JP et.al. Early prenatal diagnosis of bronchopulmonary sequestration with associated diaphragmatic hernia. J Ultrasound Med 1995;14:533-535.