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SEMILOBAR
HOLOPROSENCEPHALY |
Structural variant of the lobar type in which separation
between ventricles is partial and commonly exists in the anterior and posterior
portions of the lateral ventricle, with a common communication centrally.
It represents incomplete cleavage of the prosencephalon
(more midline differentiation with the beginning of sagittal separation).
ULTRASOUND |
- Mild facial anomalies (midline cleft lip and palate).
- Hypotelorism.
- Single ventricular chamber with partially formed occipital horns and rudimentary temporal horns.
- Peripheral rim of brain tissue several centimeters thick.
- Partially fused thalami (situated anteriorly and abnormally rotated).
- Small 3rd ventricle.
- Absent cavum septum pellucidum, corpus callosum and olfactory bulb.
- Rudimentary falx cerebri and interhemispheric fissure.
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Video clip of hypotelorism associated with semilobar
holoprosencephaly
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