- Retained products of
conception (chorionic villi = placental tissue and trophoblastic = fetal
tissue remaining within the uterus).
- Clinical signs:
- Prolonged bleeding.
- Infection.
(Accuracy ±96%)
Finding
|
Retained Products
|
Gestational
sac/collection
Gestational sac + dead fetus
Endometrium >5mm thick
Endometrium 2-5mm thick
Endometrium <2mm thick
|
100%
100%
100%
43%
14%
|
·
Variable appearance on ultrasound:
o Normal
o Mass
of mixed echogenicity.
·
Color doppler is very useful because of the varied
appearance. The presence of a prominent vascular supply and feeding vessel
helps make the diagnosis. In more chronic cases the retained products may be
avascular.
- Endometritis, myometritis,
peritonitis, septic shock, diffuse intravascular coagulopathy (DIC) with
retention >1 month.
- Endometritis –
endometrium appears prominent, irregular or both, usually with a small
amount of endometrial fluid. Clinically the patients present with severe
pelvic pain.
Neilson and Hahlin (1995) (1):
- Randomized
prospective trial of 103 women with retained products of conception (RPOC)
measuring 15-50 mm.
- 71% success rate in expectant management.
- Complication rate (measured by the number of
infections or the development of anemia):
- 3% on the expectant group.
- 11% in the surgical group.
- Duration of bleeding in the expectant group was 1.3
days longer (P<0.02).
- No difference in pain or packed cell volume in each
group.
Failure to resolve the miscarriage
was most likely when gestational sac was intact and the cervix was closed.
Resolution in these patients may take several weeks and up to 20% will opt for
surgical evacuation. The rate of spontaneous completion depends on the type:
Classification
|
Complete miscarriage
|
Successful outcome by day 46
|
By
day 7
|
By
day 14
|
Incomplete
abortion
|
53%
|
84%
|
91%
|
Missed
abortion
|
30%
|
59%
|
76%
|
Anembryonic
pregnancy
|
25%
|
52%
|
66%
|
Adapted from: Luise C, Jermy K, Collins WP, Bourne TH. Outcome of expectant
management of spontaneous first trimester miscarriage: observational study.
BMJ 2002;324:873-875.
|
Other authors have reported success
rates for expectant management of as low as 24.7 % (2).
Luise and Jermy (3):
- Neither the presence of a gestational sac within the
uterine cavity nor the thickness of the endometrium is clinically useful
in determining outcome of expectant management.
- The number of days taken to complete a miscarriage
and the proportion of women completing their miscarriage in relation to
time is not related to the initial ultrasound findings.
- Data suggests that follow up for women with incomplete
miscarriage need not include sonography.
- Neilson S, Hahlin M. Expectant management of first trimester
spontaneous abortion. Lancet 1995;345:84-86.
- Jurkovic D, Ross JA, Nicolaides KH. Expectant management of
miscarriage. Br J Obstet Gynaecol 1998;105:670-671.
- Luise C, Jermy K, Collins WP et.al. Expectant management of incomplete, spontaneous
first-trimester miscarriage; outcome according to initial ultrasound
criteria and value of follow up visits. Ultrasound Obstet Gynecol
2002;19:580-582
- Condous G, Okaro E, Bourne T. The conservative management of early
pregnancy complications. Ultrasound Obstet Gynecol 2003;22:420-430.