FETAL CAUSES OF IUGR

1. Chromosomal abnormalities.
• Normal karyotype (91.9%)
• Polyploidy (especially triploidy and tetraploidy) (3.6%).
• Trisomy 21 (1.25%).
• Trisomy 18 (1.73%).
• Trisomy 13 (0.95%).
• XO (0.17%).
2. Structural fetal malformations.
3. Multiple pregnancies.
4. Intrauterine infections.
5. Inborn errors of metabolism.
• Phenylketonuria.