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POLYHYDRAMNIOS AND
OLIGOHYDRAMNIOS
IN TRISOMY 18
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- Frequency of polyhydramnios
is age dependent.
- Not reported in the first and
early second trimesters.
- Prevalence ranges from 29-62%
in the third trimester.
- Polyhydramnios in the
presence of symmetrical IUGR suggests that a chromosomal abnormality
(especially trisomy 18) may be present as oligohydramnios usually
accompanies the IUGR that is present.
- IUGR and polyhydramnios
occurred in 21% of trisomy 18 fetuses in one series (1).
- Polyhydramnios in trisomy 18
without fetal intestinal obstruction suggests a severe central nervous
system deficit (2).
Ultrasound Diagnosis of
Polyhydramnios
Ultrasound
Diagnosis of Oligohydramnios
- Nyberg DA, Kramer D, Resta RG
et.al. Prenatal sonographic findings of trisomy 18: review of 47 cases. J
Ultrasound Med 1993;2:103-113.
- Hill LM. The sonographic
detection of trisomies 13, 18 and 21. Clin Obstet Gynecol
1996;39(4):831-850.