GREBE SYNDROME

Grebe syndrome is described among the inbred Indian tribes from Brazil.

• Autosomal recessive.

ULTRASOUND

• Marked hypomelia of upper and lower limbs.
• Increases in severity from proximal to distal segments.
• Lower limbs are more affected than upper limbs (in contrast to Robert's syndrome).

REFERENCES

1. Romero G, Zonana J, Lachman RS et.al. Grebe chondrodysplasia and similar forms of severe short limbed dwarfism. Birth Defects 1977;13:109-115.